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Evaluation of vanillin as a probe drug for aldehyde oxidase and phenotyping for its activity in a Western Indian Cohort

BACKGROUND: Aldehyde oxidase (AO), a molybdoflavoenzyme, is emerging as a key player in drug discovery and metabolism. Despite having several known substrates, there are no validated probes reported for studying the activity of AO in vivo. Vanillin (4-hydroxy 3-methoxy benzaldehyde) is an excellent...

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Detalhes bibliográficos
Publicado no:Indian J Pharmacol
Main Authors: Subash, Sandhya, Gogtay, Nithya J, Iyer, Krishna R, Gandhe, Prajakta, Budania, Ritu, Thatte, Urmila M
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262417/
https://ncbi.nlm.nih.gov/pubmed/34169906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijp.IJP_463_18
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