Minicircles for a Two-Step Blood Biomarker and PET Imaging Early Cancer Detection Strategy

Early cancer detection can dramatically increase treatment options and survival rates for patients, yet detection of early-stage tumors remains difficult. Here, we demonstrate a two-step strategy to detect and locate cancerous lesions by delivering tumor-activatable minicircle (MC) plasmids encoding...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Robinson, Elise R., Gowrishankar, Gayatri, D’Souza, Aloma, Kheirolomoom, Azadeh, Haywood, Tom, Hori, Sharon S., Chuang, Hui-Yen, Zeng, Yitian, Tumbale, Spencer, Aalipour, Amin, Beinat, Corinne, Alam, Israt S., Sathirachinda, Ataya, Kanada, Masamitsu, Paulmurugan, Ramasamy, Ferrara, Katherine W., Gambhir, Sanjiv S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262353/
https://ncbi.nlm.nih.gov/pubmed/34029631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2021.05.026
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