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DD-03 THE NATURALLY OCCURRING STEROID, WITHAFERIN A, IN SYNERGISTIC CONCERT WITH HER2/EGFR INHIBITORS ABROGATES PROLIFERATION OF HUMAN GLIOBLASTOMA CELL CULTURES AT NANOMOLAR CONCENTRATIONS
INTRODUCTION: Withaferin A, a steroidal lactone that is isolated from the winter cherry (Withania sominifera), confers abrogatory effects on proliferating cancer cells. This is achieved, partly though Withaferin A's ability to retard angiogenesis along with VEGF and calcium signaling. At the le...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218033/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou246.3 |
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