ATI-2307 Exhibits Equivalent Antifungal Activity in Cryptococcus neoformans Clinical Isolates With High and Low Fluconazole IC(50)

Half maximal inhibitory concentrations (IC(50)) to the experimental drug ATI-2307 and complete inhibition (IC(90)) of the common clinically used antifungal drug amphotericin B were determined by microbroth dilution assay for a collection of 69 clinical isolates of Cryptococcus neoformans from Uganda...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Gerlach, Elliot S., Altamirano, Sophie, Yoder, J. Marina, Luggya, Tony S., Akampurira, Andrew, Meya, David B., Boulware, David R., Rhein, Joshua, Nielsen, Kirsten
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262267/
https://ncbi.nlm.nih.gov/pubmed/34249782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.695240
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