Minimum Inhibitory Concentration Distribution of Fluconazole Against Cryptococcus Species and the Fluconazole Exposure Prediction Model

BACKGROUND: Fluconazole is lifesaving for treatment and prevention of cryptococcosis; however, optimal dosing is unknown. Initial fluconazole doses of 100 mg to 2000 mg/day have been used. Prevalence of fluconazole nonsusceptible Cryptococcus is increasing over time, risking the efficacy of long-est...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Chesdachai, Supavit, Rajasingham, Radha, Nicol, Melanie R, Meya, David B, Bongomin, Felix, Abassi, Mahsa, Skipper, Caleb, Kwizera, Richard, Rhein, Joshua, Boulware, David R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767974/
https://ncbi.nlm.nih.gov/pubmed/31420668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz369
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