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CRISPR/Cas9-mediated Knockout of SIRT6 Imparts Remarkable Anti-proliferative Response in Human Melanoma Cells in vitro and in vivo

Melanoma is one of the most aggressive, potentially fatal forms of skin cancer, and has been shown to be associated with solar ultraviolet radiation-dependent initiation and progression. Despite remarkable recent advances with targeted- and immune- therapeutics, lasting and recurrence-free survival...

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Bibliographische Detailangaben
Veröffentlicht in:Photochem Photobiol
Hauptverfasser: Garcia-Peterson, Liz M., Ndiaye, Mary A., Chhabra, Gagan, Singh, Chandra K., Guzmán-Pérez, Glorimar, Iczkowski, Kenneth A., Ahmad, Nihal
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262248/
https://ncbi.nlm.nih.gov/pubmed/32621766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.13305
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