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CRISPR/Cas9-mediated Knockout of SIRT6 Imparts Remarkable Anti-proliferative Response in Human Melanoma Cells in vitro and in vivo

Melanoma is one of the most aggressive, potentially fatal forms of skin cancer, and has been shown to be associated with solar ultraviolet radiation-dependent initiation and progression. Despite remarkable recent advances with targeted- and immune- therapeutics, lasting and recurrence-free survival...

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Detalhes bibliográficos
Publicado no:Photochem Photobiol
Principais autores: Garcia-Peterson, Liz M., Ndiaye, Mary A., Chhabra, Gagan, Singh, Chandra K., Guzmán-Pérez, Glorimar, Iczkowski, Kenneth A., Ahmad, Nihal
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262248/
https://ncbi.nlm.nih.gov/pubmed/32621766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.13305
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