HDAC Inhibition Induces Cell Cycle Arrest and Mesenchymal-Epithelial Transition in a Novel Pleural-Effusion Derived Uterine Carcinosarcoma Cell Line

Objective: Uterine carcinosarcoma (UCS) is a rare but highly aggressive malignancy with biphasic growth pattern. This morphology can be attributed to epithelial-mesenchymal transition (EMT) that often associates with tumor invasion and metastasis. Accordingly, we analyzed a novel patient-derived pre...

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Publicado en:Pathol Oncol Res
Autores principales: Stockhammer, Paul, Okumus, Özlem, Hegedus, Luca, Rittler, Dominika, Ploenes, Till, Herold, Thomas, Kalbourtzis, Stavros, Bankfalvi, Agnes, Sucker, Antje, Kimmig, Rainer, Aigner, Clemens, Hegedus, Balazs
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Society Journal Archive
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262245/
https://ncbi.nlm.nih.gov/pubmed/34257602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/pore.2021.636088
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