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The Research Progress of Direct KRAS G12C Mutation Inhibitors
Abstract: KRAS mutations have long been considered undruggable. However, a series of direct KRAS mutation inhibitors have been developed since the switch II pocket was discovered recently. This review will summarize progress in the development of direct KRAS G12C mutation inhibitors, current relevan...
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| Publié dans: | Pathol Oncol Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8262225/ https://ncbi.nlm.nih.gov/pubmed/34257597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/pore.2021.631095 |
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