Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in reproductive-age women. Excessive inflammation and elevated androgen production from ovarian theca cells are key features of PCOS. Human bone marrow mesenchymal stem cells (BM-hMSC) and their secreted...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Chugh, Rishi Man, Park, Hang-soo, El Andaloussi, Abdeljabar, Elsharoud, Amro, Esfandyari, Sahar, Ulin, Mara, Bakir, Lale, Aboalsoud, Alshimaa, Ali, Mohamed, Ashour, Dalia, Igboeli, Prosper, Ismail, Nahed, McAllister, Jan, Al-Hendy, Ayman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261924/
https://ncbi.nlm.nih.gov/pubmed/34233746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02472-w
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