Human BM-MSC secretome enhances human granulosa cell proliferation and steroidogenesis and restores ovarian function in primary ovarian insufficiency mouse model

Primary ovarian insufficiency (POI) is defined as the loss of ovarian function before 40 years of age. It clinically manifests as amenorrhea, infertility, and signs of estrogen insufficiency. POI is frequently induced by chemotherapy. Gonadotoxic chemotherapy reagents damage granulosa cells, which a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Park, Hang-soo, Chugh, Rishi Man, El Andaloussi, Abdeljabar, Hobeika, Elie, Esfandyari, Sahar, Elsharoud, Amro, Ulin, Mara, Garcia, Natalia, Bilal, Mahmood, Al-Hendy, Ayman
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907146/
https://ncbi.nlm.nih.gov/pubmed/33633319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84216-7
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares