Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms

Turnover of the primary cilium (PC) is critical for proliferation and tissue homeostasis. Each key component of the PC resorption machinery, the HEF1/Aurora kinase A (AurA)/HDAC6 pathway harbors cis-elements potentially targeted by the transcriptional co-activator myocardin-related transcription fac...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Speight, Pam, Rozycki, Matthew, Venugopal, Shruthi, Szászi, Katalin, Kofler, Michael, Kapus, András
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
https://ncbi.nlm.nih.gov/pubmed/34278253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102739
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