Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms

Turnover of the primary cilium (PC) is critical for proliferation and tissue homeostasis. Each key component of the PC resorption machinery, the HEF1/Aurora kinase A (AurA)/HDAC6 pathway harbors cis-elements potentially targeted by the transcriptional co-activator myocardin-related transcription fac...

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Publicado en:iScience
Autores principales: Speight, Pam, Rozycki, Matthew, Venugopal, Shruthi, Szászi, Katalin, Kofler, Michael, Kapus, András
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
https://ncbi.nlm.nih.gov/pubmed/34278253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102739
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