Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms

Turnover of the primary cilium (PC) is critical for proliferation and tissue homeostasis. Each key component of the PC resorption machinery, the HEF1/Aurora kinase A (AurA)/HDAC6 pathway harbors cis-elements potentially targeted by the transcriptional co-activator myocardin-related transcription fac...

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Pubblicato in:iScience
Autori principali: Speight, Pam, Rozycki, Matthew, Venugopal, Shruthi, Szászi, Katalin, Kofler, Michael, Kapus, András
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
https://ncbi.nlm.nih.gov/pubmed/34278253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102739
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