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Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms

Turnover of the primary cilium (PC) is critical for proliferation and tissue homeostasis. Each key component of the PC resorption machinery, the HEF1/Aurora kinase A (AurA)/HDAC6 pathway harbors cis-elements potentially targeted by the transcriptional co-activator myocardin-related transcription fac...

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Enregistré dans:
Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Speight, Pam, Rozycki, Matthew, Venugopal, Shruthi, Szászi, Katalin, Kofler, Michael, Kapus, András
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
https://ncbi.nlm.nih.gov/pubmed/34278253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102739
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