Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms

Turnover of the primary cilium (PC) is critical for proliferation and tissue homeostasis. Each key component of the PC resorption machinery, the HEF1/Aurora kinase A (AurA)/HDAC6 pathway harbors cis-elements potentially targeted by the transcriptional co-activator myocardin-related transcription fac...

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Vydáno v:iScience
Hlavní autoři: Speight, Pam, Rozycki, Matthew, Venugopal, Shruthi, Szászi, Katalin, Kofler, Michael, Kapus, András
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
https://ncbi.nlm.nih.gov/pubmed/34278253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102739
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