The Curcumin Analog GO-Y030 Controls the Generation and Stability of Regulatory T Cells

Regulatory T cells (Tregs) play a crucial role in preventing antitumor immune responses in cancer tissues. Cancer tissues produce large amounts of transforming growth factor beta (TGF-β), which promotes the generation of Foxp3(+) Tregs from naïve CD4(+) T cells in the local tumor microenvironment. T...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: MaruYama, Takashi, Kobayashi, Shuhei, Nakatsukasa, Hiroko, Moritoki, Yuki, Taguchi, Daiki, Sunagawa, Yoichi, Morimoto, Tatsuya, Asao, Atsuko, Jin, Wenwen, Owada, Yuji, Ishii, Naoto, Iwabuchi, Yoshiharu, Yoshimura, Akihiko, Chen, WanJun, Shibata, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261301/
https://ncbi.nlm.nih.gov/pubmed/34248973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.687669
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