The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice

Curcumin is a naturally occurring p300-histone acetyltransferase (p300-HAT) inhibitor that suppresses cardiomyocyte hypertrophy and the development of heart failure in experimental animal models. To enhance the therapeutic potential of curcumin against heart failure, we produced a series of syntheti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Shimizu, Kana, Sunagawa, Yoichi, Funamoto, Masafumi, Wakabayashi, Hiroki, Genpei, Mai, Miyazaki, Yusuke, Katanasaka, Yasufumi, Sari, Nurmila, Shimizu, Satoshi, Katayama, Ayumi, Shibata, Hiroyuki, Iwabuchi, Yoshiharu, Kakeya, Hideaki, Wada, Hiromichi, Hasegawa, Koji, Morimoto, Tatsuya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188884/
https://ncbi.nlm.nih.gov/pubmed/32346115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64207-w
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