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Targeting Bruton’s Tyrosine Kinase in CLL

Targeting the B-cell receptor signaling pathway through BTK inhibition proved to be effective for the treatment of chronic lymphocytic leukemia (CLL) and other B-cell lymphomas. Covalent BTK inhibitors (BTKis) led to an unprecedented improvement in outcome in CLL, in particular for high-risk subgrou...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Ahn, Inhye E., Brown, Jennifer R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261291/
https://ncbi.nlm.nih.gov/pubmed/34248972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.687458
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