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Targeting Bruton’s Tyrosine Kinase in CLL
Targeting the B-cell receptor signaling pathway through BTK inhibition proved to be effective for the treatment of chronic lymphocytic leukemia (CLL) and other B-cell lymphomas. Covalent BTK inhibitors (BTKis) led to an unprecedented improvement in outcome in CLL, in particular for high-risk subgrou...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8261291/ https://ncbi.nlm.nih.gov/pubmed/34248972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.687458 |
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