Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel

Most biopharmaceutics classification system (BCS) class IV drugs, with poor solubility and inferior permeability, are also substrates of P-glycoprotein (P-gp) and cytochrome P450 (CYP450), leading to their low oral bioavailability. The objective of this study is to explore the potential of using fun...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Asian J Pharm Sci
Päätekijät: Qin, Lu, Wu, Haiyang, Xu, Enyu, Zhang, Xin, Guan, Jian, Zhao, Ruizhi, Mao, Shirui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Shenyang Pharmaceutical University 2021
Aiheet:
Original Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261254/
https://ncbi.nlm.nih.gov/pubmed/34276826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2021.02.004
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