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GMP-compliant production of [(68)Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

BACKGROUND: [(68)Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [(68)Ga]Ga-NeoB using a GMP...

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Dettagli Bibliografici
Pubblicato in:EJNMMI Radiopharm Chem
Autori principali: Pretze, Marc, Reffert, Laura, Diehl, Steffen, Schönberg, Stefan O., Wängler, Carmen, Hohenberger, Peter, Wängler, Björn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260665/
https://ncbi.nlm.nih.gov/pubmed/34228236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-021-00137-w
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