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GMP-compliant production of [(68)Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

BACKGROUND: [(68)Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [(68)Ga]Ga-NeoB using a GMP...

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Detalhes bibliográficos
Publicado no:EJNMMI Radiopharm Chem
Main Authors: Pretze, Marc, Reffert, Laura, Diehl, Steffen, Schönberg, Stefan O., Wängler, Carmen, Hohenberger, Peter, Wängler, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260665/
https://ncbi.nlm.nih.gov/pubmed/34228236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-021-00137-w
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