Nampt controls skeletal muscle development by maintaining Ca(2+) homeostasis and mitochondrial integrity

OBJECTIVE: NAD(+) is a co-factor and substrate for enzymes maintaining energy homeostasis. Nicotinamide phosphoribosyltransferase (NAMPT) controls NAD(+) synthesis, and in skeletal muscle, NAD(+) is essential for muscle integrity. However, the underlying molecular mechanisms by which NAD(+) synthesi...

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Pubblicato in:Mol Metab
Autori principali: Basse, Astrid L., Agerholm, Marianne, Farup, Jean, Dalbram, Emilie, Nielsen, Joachim, Ørtenblad, Niels, Altıntaş, Ali, Ehrlich, Amy M., Krag, Thomas, Bruzzone, Santina, Dall, Morten, de Guia, Roldan M., Jensen, Jonas B., Møller, Andreas B., Karlsen, Anders, Kjær, Michael, Barrès, Romain, Vissing, John, Larsen, Steen, Jessen, Niels, Treebak, Jonas T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259345/
https://ncbi.nlm.nih.gov/pubmed/34119711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101271
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