Nampt controls skeletal muscle development by maintaining Ca(2+) homeostasis and mitochondrial integrity

OBJECTIVE: NAD(+) is a co-factor and substrate for enzymes maintaining energy homeostasis. Nicotinamide phosphoribosyltransferase (NAMPT) controls NAD(+) synthesis, and in skeletal muscle, NAD(+) is essential for muscle integrity. However, the underlying molecular mechanisms by which NAD(+) synthesi...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Basse, Astrid L., Agerholm, Marianne, Farup, Jean, Dalbram, Emilie, Nielsen, Joachim, Ørtenblad, Niels, Altıntaş, Ali, Ehrlich, Amy M., Krag, Thomas, Bruzzone, Santina, Dall, Morten, de Guia, Roldan M., Jensen, Jonas B., Møller, Andreas B., Karlsen, Anders, Kjær, Michael, Barrès, Romain, Vissing, John, Larsen, Steen, Jessen, Niels, Treebak, Jonas T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259345/
https://ncbi.nlm.nih.gov/pubmed/34119711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101271
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