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Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway

BACKGROUND: Several studies have reported that hypoxia plays a pathological role in severe asthma and tissue fibrosis. Our previous study showed that hypoxia induces A disintegrin and metalloproteinase 17 (ADAM17) expression in human lung fibroblasts. Moreover, preadipocyte factor 1 (Pref-1) is clea...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Cheng, Wun-Hao, Chen, Chia-Ling, Chen, Jing-Yun, Lin, Chien-Huang, Chen, Bing-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259210/
https://ncbi.nlm.nih.gov/pubmed/34229599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-021-00336-w
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