Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response

BACKGROUND: Traumatic brain injury (TBI) is a leading cause of death and disability that lacks neuroprotective therapies. Following a TBI, secondary injury response pathways are activated and contribute to ongoing neurodegeneration. Microglia and astrocytes are critical neuroimmune modulators with e...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Todd, Brittany P., Chimenti, Michael S., Luo, Zili, Ferguson, Polly J., Bassuk, Alexander G., Newell, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259035/
https://ncbi.nlm.nih.gov/pubmed/34225752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02197-w
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