Combined Blockade of Interleukin-1α and -1β Signaling Protects Mice from Cognitive Dysfunction after Traumatic Brain Injury

Diffuse activation of interleukin-1 inflammatory cytokine signaling after traumatic brain injury (TBI) elicits progressive neurodegeneration and neuropsychiatric dysfunction, and thus represents a potential opportunity for therapeutic intervention. Although interleukin (IL)-1α and IL-1β both activat...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Newell, Elizabeth A., Todd, Brittany P., Mahoney, Jolonda, Pieper, Andrew A., Ferguson, Polly J., Bassuk, Alexander G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898697/
https://ncbi.nlm.nih.gov/pubmed/29662944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0385-17.2018
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