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Variant WWTR1 Gene Fusions in Epithelioid Hemangioendothelioma – A Genetic Subset Associated with Cardiac Involvement
The genetic hallmark of epithelioid hemangioendothelioma (EHE) is a recurrent WWTR1-CAMTA1 fusion, which is present in most cases bearing a conventional histology. A subset of cases is characterized by a distinct morphology and harbors instead a YAP1-TFE3 fusion. Nevertheless, isolated cases lack th...
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| Publicado no: | Genes Chromosomes Cancer |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8258701/ https://ncbi.nlm.nih.gov/pubmed/32170768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22839 |
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