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Variant WWTR1 Gene Fusions in Epithelioid Hemangioendothelioma – A Genetic Subset Associated with Cardiac Involvement

The genetic hallmark of epithelioid hemangioendothelioma (EHE) is a recurrent WWTR1-CAMTA1 fusion, which is present in most cases bearing a conventional histology. A subset of cases is characterized by a distinct morphology and harbors instead a YAP1-TFE3 fusion. Nevertheless, isolated cases lack th...

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書誌詳細
出版年:Genes Chromosomes Cancer
主要な著者: Suurmeijer, Albert J.H., Dickson, Brendan C., Swanson, David, Sung, Yun-Shao, Zhang, Lei, Antonescu, Cristina R.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258701/
https://ncbi.nlm.nih.gov/pubmed/32170768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22839
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