Efficient pre-treatment for pancreatic cancer using chloroquine-loaded nanoparticles targeting pancreatic stellate cells

Pancreatic stellate cells (PSCs) play a key role in desmoplastic stroma, which is a characteristic of pancreatic ductal adenocarcinoma (PDAC), and they also enhance the malignancy of pancreatic cancer cells. Our previous study reported chloroquine's mitigating effects on PSC activation; however...

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Pubblicato in:Oncol Lett
Autori principali: Matsumoto, Sokichi, Nakata, Kohei, Sagara, Akiko, Guan, Weiyu, Ikenaga, Naoki, Ohuchida, Kenoki, Nakamura, Masafumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258615/
https://ncbi.nlm.nih.gov/pubmed/34267825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12894
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