Pharmacokinetics and complementary evaluation system-based guidance on prophylaxis of paediatric patients with haemophilia A in China with Kovaltry: protocol of the LEAP study

INTRODUCTION: Haemophilia A is a rare inherited bleeding disease caused by the deficiency of coagulation factor VIII (FVIII). The main treatment protocol is to administer regular exogenous FVIII concentrate infusions. With the discovery of variability in individualised pharmacokinetics (PK) and blee...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: Kun, Huang, Xu, Weiqun, Zhou, Min, Li, Xiaojing, Xu, Zhongjin, Fang, Yongjun, Li, Changgang, Chen, Zhenping, Wu, Runhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2021
Soggetti:
Haematology (Incl Blood Transfusion)
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258559/
https://ncbi.nlm.nih.gov/pubmed/34226228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-048432
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