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Pharmacokinetics and complementary evaluation system-based guidance on prophylaxis of paediatric patients with haemophilia A in China with Kovaltry: protocol of the LEAP study

INTRODUCTION: Haemophilia A is a rare inherited bleeding disease caused by the deficiency of coagulation factor VIII (FVIII). The main treatment protocol is to administer regular exogenous FVIII concentrate infusions. With the discovery of variability in individualised pharmacokinetics (PK) and blee...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Kun, Huang, Xu, Weiqun, Zhou, Min, Li, Xiaojing, Xu, Zhongjin, Fang, Yongjun, Li, Changgang, Chen, Zhenping, Wu, Runhui
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258559/
https://ncbi.nlm.nih.gov/pubmed/34226228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-048432
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