Pharmacokinetics and complementary evaluation system-based guidance on prophylaxis of paediatric patients with haemophilia A in China with Kovaltry: protocol of the LEAP study

INTRODUCTION: Haemophilia A is a rare inherited bleeding disease caused by the deficiency of coagulation factor VIII (FVIII). The main treatment protocol is to administer regular exogenous FVIII concentrate infusions. With the discovery of variability in individualised pharmacokinetics (PK) and blee...

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Dades bibliogràfiques
Publicat a:BMJ Open
Autors principals: Kun, Huang, Xu, Weiqun, Zhou, Min, Li, Xiaojing, Xu, Zhongjin, Fang, Yongjun, Li, Changgang, Chen, Zhenping, Wu, Runhui
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2021
Matèries:
Haematology (Incl Blood Transfusion)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258559/
https://ncbi.nlm.nih.gov/pubmed/34226228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-048432
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