SIRT6 Promotes Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells Through Antagonizing DNMT1

BACKGROUND: Adipose-derived stem cells (ADSCs) are increasingly used in regenerative medicine because of their potential to differentiate into multiple cell types, including osteogenic lineages. Sirtuin protein 6 (SIRT6) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that plays i...

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Publicat a:Front Cell Dev Biol
Autors principals: Jia, Bo, Chen, Jun, Wang, Qin, Sun, Xiang, Han, Jiusong, Guastaldi, Fernando, Xiang, Shijian, Ye, Qingsong, He, Yan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258422/
https://ncbi.nlm.nih.gov/pubmed/34239868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.648627
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