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Puma- and Caspase9-mediated apoptosis is dispensable for p53-driven neural crest-based developmental defects

Inappropriate activation of the p53 transcription factor is thought to contribute to the developmental phenotypes in a range of genetic syndromes. Whether p53 activation drives these developmental phenotypes by triggering apoptosis, cell cycle arrest, or other p53 cellular responses, however, has re...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Bowen, Margot E., Mulligan, Abigail S., Sorayya, Aryo, Attardi, Laura D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257737/
https://ncbi.nlm.nih.gov/pubmed/33574585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-021-00738-7
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