Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

To date, no study has demonstrated that soluble Fas ligand (sFasL)-mediated inflammation is regulated via interaction with Fas in vivo. We found that FasL interacts specifically with tumor necrosis factor receptor superfamily (TNFRSF)10B, also known as death receptor (DR)5. Autoantibody-induced arth...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Jeong, Dongjin, Kim, Hye Sung, Kim, Hye Young, Kang, Min Jueng, Jung, Hyeryeon, Oh, Yumi, Kim, Donghyun, Koh, Jaemoon, Cho, Sung-Yup, Jeon, Yoon Kyung, Lee, Eun Bong, Lee, Seung Hyo, Shin, Eui-Cheol, Kim, Ho Min, Yi, Eugene C, Chung, Doo Hyun
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2021
Assuntos:
Immunology and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257255/
https://ncbi.nlm.nih.gov/pubmed/34223817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48840
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