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Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

BACKGROUND: Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure. There has been a lack of methods to mimic the in vivo co-occurrence, where cells and parasites can be grown together for...

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Detalles Bibliográficos
Publicado en:Malar J
Main Authors: Reddy, Sreenivasulu B., Nagy, Noemi, Rönnberg, Caroline, Chiodi, Francesca, Lugaajju, Allan, Heuts, Frank, Szekely, Laszlo, Wahlgren, Mats, Persson, Kristina E. M.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256226/
https://ncbi.nlm.nih.gov/pubmed/34225761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-021-03831-x
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