Identification of a Polyclonal B-Cell Activator in Plasmodium falciparum

Polyclonal B-cell activation and hypergammaglobulinemia are prominent features of human malaria. We report here that Plasmodium falciparum-infected erythrocytes directly adhere to and activate peripheral blood B cells from nonimmune donors. The infected erythrocytes employ the cysteine-rich interdom...

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Detalhes bibliográficos
Main Authors: Donati, Daria, Zhang, Li Ping, Chen, Qijun, Chêne, Arnaud, Flick, Kirsten, Nyström, Maja, Wahlgren, Mats, Bejarano, Maria Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517431/
https://ncbi.nlm.nih.gov/pubmed/15322039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5412-5418.2004
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