Comparative Proteomic Analysis Reveals Varying Impact on Immune Responses in Phorbol 12-Myristate-13-Acetate-Mediated THP-1 Monocyte-to-Macrophage Differentiation

Macrophages are sentinels of the innate immune system, and the human monocytic cell line THP-1 is one of the widely used in vitro models to study inflammatory processes and immune responses. Several monocyte-to-macrophage differentiation protocols exist, with phorbol 12-myristate-13-acetate (PMA) be...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pinto, Sneha M., Kim, Hera, Subbannayya, Yashwanth, Giambelluca, Miriam S., Bösl, Korbinian, Ryan, Liv, Sharma, Animesh, Kandasamy, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255674/
https://ncbi.nlm.nih.gov/pubmed/34234780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679458
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