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Actions of Thyroid Hormones on Thyroid Cancers
L-Thyroxine (T4) is the principal ligand of the thyroid hormone analogue receptor on the extracellular domain of integrin αvβ3. The integrin is overexpressed and activated in cancer cells, rapidly dividing endothelial cells, and platelets. The biologic result is that T4 at physiological concentratio...
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| I publikationen: | Front Endocrinol (Lausanne) |
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| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Frontiers Media S.A.
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8255668/ https://ncbi.nlm.nih.gov/pubmed/34234745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.691736 |
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