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Bioactivity of Thyroid Hormone Analogs at Cancer Cells

In the context of genomic thyroid hormone actions in normal (noncancer) cells that involve primary interactions with nuclear thyroid hormone receptors (TRs), L-thyroxine (T4), and 3,3′,5′-triiodo-L-thyronine (reverse T3, rT3) have little bioactivity. In terms of TRs, T4 is a prohormone from which th...

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Dades bibliogràfiques
Publicat a:Front Endocrinol (Lausanne)
Autors principals: Davis, Paul J., Tang, Heng-Yuan, Hercbergs, Aleck, Lin, Hung-Yun, Keating, Kelly A., Mousa, Shaker A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288194/
https://ncbi.nlm.nih.gov/pubmed/30564196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00739
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