Llwytho...

A novel germline BRCA1 mutation identified in a family with hereditary breast and ovarian cancer syndrome

Pathogenic germline mutations occurring in the BRCA1 (MIM:113705) and BRCA2 (MIM: 600185), which always result in truncated protein or nonsense-mediated mRNA decay, have been identified to increase the risk of hereditary breast, ovarian, pancreatic, prostate, and melanoma cancers. Recent studies sho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Med Insights Oncol
Prif Awduron: Wu, Yanmei, Pan, Xiaodong, Dou, Juan, Zhang, Quan, Li, Yuantong, Sheng, Yuan, Liu, Xishui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255550/
https://ncbi.nlm.nih.gov/pubmed/34276234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/11795549211028569
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!