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OTME-15. Physical Confinement Induces Diverse Transcriptomic Changes and Chemoresistance in Migrating Glioblastoma Cells

Glioblastoma multiforme (GBM) cells migrating in physically confined environments are affected by mechanical stress that potentially lead to transcriptomic changes. To simulate those stresses, microfluidic channels were made with micro-patterned polydimethylsiloxane (PDMS) replicating the physical m...

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Foilsithe in:Neurooncol Adv
Main Authors: Battiste, James, Babu, Anish, Sharp, Rachel, Scott, Sydney, Dunn, Ian, Glenn, Chad, Kim, Young-tae, Jones, Kenneth
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255428/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.066
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