Physical Confinement during Cancer Cell Migration Triggers Therapeutic Resistance and Cancer Stem Cell-like Behavior

Metastasized cancer cells have an increased resistance to therapies leading to a drastic decrease in patient survival rates. However, our understanding of the cause for this enhanced resistance is lacking. In this study, we report that physically tight confinement during cancer cell migration trigge...

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Pubblicato in:Cancer Lett
Autori principali: Shen, Qionghua, Hill, Tamara, Cai, Xue, Bui, Loan, Barakat, Rami, Hills, Emily, Almugaiteeb, Turki, Babu, Anish, Mckernan, Patrick H, Zalles, Michelle, Battiste, James D, Kim, Young-Tae
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112468/
https://ncbi.nlm.nih.gov/pubmed/33639204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2021.01.020
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