Physical Confinement during Cancer Cell Migration Triggers Therapeutic Resistance and Cancer Stem Cell-like Behavior

Metastasized cancer cells have an increased resistance to therapies leading to a drastic decrease in patient survival rates. However, our understanding of the cause for this enhanced resistance is lacking. In this study, we report that physically tight confinement during cancer cell migration trigge...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Shen, Qionghua, Hill, Tamara, Cai, Xue, Bui, Loan, Barakat, Rami, Hills, Emily, Almugaiteeb, Turki, Babu, Anish, Mckernan, Patrick H, Zalles, Michelle, Battiste, James D, Kim, Young-Tae
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112468/
https://ncbi.nlm.nih.gov/pubmed/33639204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2021.01.020
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