Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer’s disease in Caribbean Hispanics

BACKGROUND: Genetic studies have primarily been conducted in European ancestry populations, identifying dozens of loci associated with late-onset Alzheimer’s disease (AD). However, much of AD’s heritability remains unexplained; as the prevalence of AD varies across populations, the genetic architect...

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Udgivet i:Alzheimers Res Ther
Main Authors: Horimoto, Andréa R. V. R., Xue, Diane, Thornton, Timothy A., Blue, Elizabeth E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
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Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254995/
https://ncbi.nlm.nih.gov/pubmed/34217363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00866-9
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