UHPLC-QQQ-MS/MS assay for the quantification of dianthrones as potential toxic markers of Polygonum multiflorum Thunb: applications for the standardization of traditional Chinese medicines (TCMs) with endogenous toxicity

BACKGROUND: The raw and processed roots of Polygonum multiflorum Thunb (PM) are commonly used in clinical practice to treat diverse diseases; however, reports of hepatotoxicity induced by Polygoni Multiflori Radix (PMR) and Polygoni Multiflori Radix Praeparata (PMRP) have emerged worldwide. Thus, it...

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Bibliographic Details
Published in:Chin Med
Main Authors: Yang, Jian-Bo, Song, Yun-Fei, Liu, Yue, Gao, Hui-Yu, Wang, Qi, Wang, Ying, Cheng, Xian-Long, Zuo, Tian-Tian, Hu, Xiao-Wen, Wei, Feng, Jin, Hong-Tao, Wang, Shu-Ting, Ma, Shuang-Cheng
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254911/
https://ncbi.nlm.nih.gov/pubmed/34217329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-021-00463-w
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