WNK1 is an assembly factor for the human ER membrane protein complex

The assembly of nascent proteins into multi-subunit complexes is a tightly regulated process which must occur at high fidelity to maintain cellular homeostasis. The ER membrane protein complex (EMC) is an essential insertase that requires seven membrane-spanning and two soluble cytosolic subunits fo...

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Gepubliceerd in:Mol Cell
Hoofdauteurs: Pleiner, Tino, Hazu, Masami, Tomaleri, Giovani Pinton, Januszyk, Kurt, Oania, Robert S., Sweredoski, Michael J., Moradian, Annie, Guna, Alina, Voorhees, Rebecca M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254792/
https://ncbi.nlm.nih.gov/pubmed/33964204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.04.013
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