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Structural basis for membrane insertion by the human ER membrane protein complex

A defining step in the biogenesis of a membrane protein is the insertion of its hydrophobic transmembrane helices into the lipid bilayer. The nine-subunit ER membrane protein complex (EMC) is a conserved co- and post-translational insertase at the endoplasmic reticulum. We determined the structure o...

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Bibliografski detalji
Izdano u:Science
Glavni autori: Pleiner, Tino, Tomaleri, Giovani Pinton, Januszyk, Kurt, Inglis, Alison J., Hazu, Masami, Voorhees, Rebecca M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547852/
https://ncbi.nlm.nih.gov/pubmed/32439656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb5008
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