Targeted deep sequencing of bladder tumors reveals novel associations between cancer gene mutations and mutational signatures with major risk factors

PURPOSE: Exome and whole-genome sequencing of muscle-invasive bladder cancer (BC) has revealed important insights into the molecular landscape; however, there are few studies of non-muscle invasive BC with detailed risk factor information. EXPERIMENTAL DESIGN: We examined the relationship between sm...

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I publikationen:Clin Cancer Res
Huvudupphovsmän: Koutros, Stella, Rao, Nina, Moore, Lee E., Nickerson, Michael L., Lee, Donghyuk, Zhu, Bin, Pardo, Larissa A., Baris, Dalsu, Schwenn, Molly, Johnson, Alison, Jones, Kristine, Garcia-Closas, Montserrat, Prokunina-Olsson, Ludmila, Silverman, Debra T., Rothman, Nathaniel, Dean, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254772/
https://ncbi.nlm.nih.gov/pubmed/33849962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4419
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