Cannabidiol prevents lipopolysaccharide-induced sickness behavior and alters cytokine and neurotrophic factor levels in the brain

BACKGROUND: Major depressive disorder (MDD) affects millions of people worldwide. While the exact pathogenesis is yet to be elucidated, the role of neuro-immune signaling has recently emerged. Despite major advances in pharmacotherapy, antidepressant use is marred by limited efficacy and potential s...

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Vydáno v:Pharmacol Rep
Hlavní autoři: Tito, Pedro Augusto Lopes, Bernardino, Túlio Cézar de Souza, Bellozi, Paula Maria Quaglio, da Silva, Maria Carolina Machado, de Miranda, Aline Silva, Vieira, Érica Leandro Marciano, Moreira, Fabrício A., Palotás, András, de Oliveira, Antônio Carlos Pinheiro, Reis, Helton José
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254454/
https://ncbi.nlm.nih.gov/pubmed/34218397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-021-00301-8
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