A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis

BACKGROUND: During eye lens development the embryonic vasculature regresses leaving the lens without a direct oxygen source. Both embryonically and throughout adult life, the lens contains a decreasing oxygen gradient from the surface to the core that parallels the natural differentiation of immatur...

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Foilsithe in:BMC Genomics
Main Authors: Disatham, Joshua, Brennan, Lisa, Chauss, Daniel, Kantorow, Jason, Afzali, Behdad, Kantorow, Marc
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2021
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254356/
https://ncbi.nlm.nih.gov/pubmed/34215186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07795-9
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